Understanding Syphilis Blood Testing

This blood test screens for syphilis. If the screen is positive, the lab automatically runs confirmatory testing, so one draw gives a clear answer.

How the Test Works

Syphilis blood testing uses two types of tests together for accuracy. This panel combines them with automatic follow-up.

Component What It Means
RPRScreening Test Detects the body’s general response to a syphilis infection. A positive result reflexes to a titer and a confirmatory test.
TiterMeasure of Activity A number that reflects how active the infection is. It is also used to track response to treatment over time.
Treponemal AntibodyConfirmation A syphilis-specific antibody test that confirms whether the RPR reflects a true infection.

What Your Results Can Mean

Result What It Means
NegativeNo Syphilis Detected No sign of syphilis.
Positive (Confirmed)Syphilis Detected Confirmatory testing supports syphilis. It is fully curable with antibiotics, and the titer helps guide and monitor treatment.

What’s Most Important to Know

Syphilis has been rising and often has no symptoms, so blood screening is an important part of sexual health care.

A positive result is very treatable. Dr. Mui will arrange treatment, repeat titers to confirm it worked, and discuss partner testing confidentially.

This page is for general education and does not replace a conversation with your doctor about your specific results. Want to review your results? Book a visit and we’ll go through them together.